Cellular therapy following allogeneic stem-cell transplantation
نویسندگان
چکیده
منابع مشابه
Undifferentiated spondyloarthritis following allogeneic stem cell transplantation
BACKGROUND Stem cell transplant has been utilized in the treatment of malignancies and rheumatic disease. Rheumatic disease may be transferred from the donor with active disease or may be developed in a recipient de novo as a late complication of SCT. CASE PRESENTATION We here report the rare case of a 26-year old male patient, who has been diagnosed with undifferentiated spondyloarthropathy ...
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Wernicke's encephalopathy is caused by thiamine deficiency, and is characterized by acute mental confusion, ataxia, and ophthalmoplegia. It is also a rare neurologic complication of hematopoietic stem cell transplantation (HSCT). However, because of its rare incidence, Wernicke's encephalopathy can easily be overlooked in HSCT patients, and a few misleading steps in the early stage of the disea...
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PURPOSE OF REVIEW The aim of this article is to assess the current understanding and uncertainties about the evaluation and management of thrombotic microangiopathy that occurs following allogeneic hematopoietic stem cell transplantation. RECENT FINDINGS Current data may not be sufficient to establish posttransplantation thrombotic microangiopathy as a discrete clinical or pathologic entity, ...
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We would like to comment on the recent report by Chakrabarti et al 1 on the risk of cytomegalovirus (CMV) infection following nonmyeloablative allogeneic transplantation. The conditioning regimen utilized by the authors consisted of fludarabine, melpha-lan, and a total dose of 100 mg of alemtuzumab (Campath-1H) given over 5 days. They found an 84.3% probability of CMV infection in patients at h...
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DNA methylation and other epigenetic phenomena appear to be relevant in the pathogenesis of several malignant disorders. DNA methyltransferases add methyl groups to cytosine-phosphate-guanine (CpG) islandsleading to gene promoter silencing. The DNA methyltransferases inhibitors azacitidine and decitabine have anti-tumor activity against a broad range of malignancies, but have been investigated ...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Hematology
سال: 2011
ISSN: 2040-6207,2040-6215
DOI: 10.1177/2040620711412416